Crosslinking Reagents
Cayman Chemical AdenylosuccInIc AcId 50mg
A purine nucleotide and an intermediate in the purine nucleotide cycle; converted into AMP and fumarate by ADSL in the cytosol; inhibits calcium-induced activation of non-selective cation channels in isolated rat brown adipocytes in a patch-clamp assay at 10 µM; induces contractions in isolated guinea pig uterus strips at 100 µM; increases glucose-induced insulin exocytosis in INS-1 832/13 insulinoma cells at 10 µM; decreases muscle damage and pseudohypertrophy in a dystrophin-deficient mdx mouse model of DMD
FOCUS BIOMOLECULES Biochemical Reagents, Mitomycin C, DNA crosslinking and damaging agent, CAS 50-07-7, 98% by TLC/NMR Conforms
Biochemical Reagents, Mitomycin C, DNA crosslinking and damaging agent, CAS 50-07-7, 98% by TLC/NMR Conforms, DNA damaging and crosslinking agent. Induces apoptosis in various cell lines. Cell permeable.This product is not approved for human therapeutic use.
Cayman Chemical MIsoprostolfree acId 50mg
Misoprostol is a prostaglandin E1 (Item No. 13010) analog with agonist activity mediated by EP2, EP3, and EP4 receptors. It has been shown to inhibit the formation of gastric lesions in rats (ED50 = 0.31 UG/kg),{1754} inhibit superoxide generation in human neutrophils (EC50 = 0.35 µM), and relax fetal rabbit ductus arteriosus (EC50 = 0.36 nM) in a concentration dependent manner. Misoprostol is commonly used in clinical medicine for the prevention of peptic ulcer disease. It has also been used in conjunction with mifepristone (RU-486; Item No. 10006317) for the oral induction of first trimester abortion. Misoprostol contains a C-1 methyl ester and is readily absorbed and rapidly hydrolyzed in humans to the active free acid.{2313}
Cayman Chemical AdrenIc AcId 50mg
A naturally occurring PUFA formed through a 2-carbon chain elongation of arachidonic acid; present in the adrenal glands, brain, testis, and kidney
Cayman Chemical Sulfo-SMCCsodIum salt 250mg
A water-soluble protein cross-linking reagent; has been used to conjugate anti-PD-L1 antibodies to the surface of platelets and Golgi-targeting peptides to platelet microparticle-mimetic nanoplatforms
Cayman Chemical MItochonIc AcId 5 50mg
An inhibitor of mitochondrial dysfunction; increases intracellular ATP levels in Hep3B cells at a 3 µM; rescues LPS-induced apoptosis and decreases in the mitochondrial membrane potential in BV-2 microglial cells at 5 µM; protects against BSO-induced decreases in cell viability in fibroblasts isolated from patients with various mitochondrial diseases (EC50s = 2.3-5.1 µM) in an electron transport chain-independent manner; reduces plasma levels of creatinine and decreases acute renal tubular necrosis in a mouse model of bilateral retroperitoneal renal ischemia-reperfusion injury at 50 mg/kg
eMolecules TargetMol DSG Crosslinker 500mg 726066256 T15171 0 000 79642-50-5 MFCD00153597 326 261 C13H14N2O8
TargetMol DSG Crosslinker 500mg 726066256 T15171 0 000 79642-50-5 MFCD00153597 326 261 C13H14N2O8
Cayman Chemical 2propyl4PentenoIc AcId 50mg
A metabolite of valproic acid; undergoes β-oxidation to form reactive metabolites that induce hepatotoxicity in rats; neuroteratogenic, reducing forebrain size and inducing deformation of the neural tube in mouse embryos
Cayman Chemical PerfluoroctnsulfonIc AcId 50mg
A perfluoroalkyl substance; decreases PPARγ transactivation in a reporter assay and induces apoptosis in NRK-52E cells at 50 nM, effects that can be reversed by rosiglitazone; increases MDA levels and decreases GSH levels in zebrafish larvae at 20 mg/L; decreases body weight and induces hepatomegaly, renal hypertrophy, neoplastic growth in the gonads, thickening of pulmonary epithelial walls, and focal hyperplasia of cerebral gliocytes in rats at 20 mg/kg; maternal serum exposure is positively associated with gestational diabetes and umbilical cord serum levels are negatively associated with infant birth weight and head circumference; has been found in lake trout, marine mammals, and urban watersheds
Cayman Chemical C-ReactIve ProteInhumnre 200ug
Source: Recombinant human C-reactive protein expressed in HEK293 cells • Amino acids: 19-224 • MW: 23 kDa
Cayman Chemical 12-TrIdecenoIc AcId 50mg
A monounsaturated fatty acid; active against S. aureus (MIC = 1.17 mM); inhibits gastric juice secretion in a rat model of pylorus ligation-induced gastric ulcers at 5, 10, and 25 mg/kg
Cell Signaling Technology CAR G4S Linker Antigen Density Quantitation Kit PE 1 Kit
CAR G4S Linker Antigen Density Quantitation Kit PE 1 Kit
Cell Signaling Technology G4S Linker E7O2V Human Chimeric mAb 20 ul
G4S Linker E7O2V Human Chimeric mAb 20 ul